EP327: Pharma Hooking Up With Start-ups, With Naomi Fried, PhD, About PharmStars™
June 24, 2021
327
32:25

EP327: Pharma Hooking Up With Start-ups, With Naomi Fried, PhD, About PharmStars™

You can subscribe to this show two ways. One way is through the iTunes podcast app or your podcast app of choice. That’s a cool way to subscribe because then the show just kind of turns up in your podcast app each week and you can decide to listen to it on the fly. The other way is to subscribe on our Web site. This is more like a newsletter subscription. If you subscribe this way, you get an email each week that transcribes the show introduction, plus includes timed show notes. Many people subscribe both ways, just saying, because each way has different benefits that are pretty complementary. If you subscribe to the newsletter, you only get the newsletter. We are frankly way too busy doing other things to send out other emails. Also, you can easily unsubscribe at any time.

I saw a post the other day in Twitter. Someone wrote, “So much can be done to improve community and share lessons to improve outcomes. The trick is making money without selling patient data to Pharma.”

Here’s my question for you, and I’m legit asking: I have seen many use cases that benefit patients and that are incredibly worthwhile. But no one is willing to pay for them. That’s the first point this Tweet I just read infers.

And I’ve seen it time and time again: gaps in care no one is willing to fill. If you’re speaking about very specific patient populations in very specific therapeutic categories, like some rare diseases, you’re not going to find basically anyone besides Pharma who has the bandwidth, the money, the expertise, and the reach to fill that gap.

If you contemplate this further, and I have, Pharma might be the only entity who, if they do it, the price of health care doesn’t immediately go up. Hear me out here because I’m wading into controversial waters, so let me make my point before you jump me in a dark alley.

If Pharma does something and it comes out of their existing marketing budget or their R&D budget or some other existing budget, them spending money on filling a patient gap versus them spending money on some TV ad is not going to impact the price of the drug either way. If the price of the drug is already too high, the price of the drug is still too high. That’s going to be true regardless. Why not let Pharma pay the freight for making sure their own patient populations get the best care possible?

This show is posted on LinkedIn and Twitter. Let me know what your thoughts are. I’m very interested.

In this health care podcast, I am really pleased to be speaking with Naomi Fried, PhD. Dr. Fried has had and continues to have a storied career. Each of her roles has always circled around innovation. She’s been the chief innovation officer at Boston Children’s, where she built their first digital health accelerator. She was recruited by Biogen after that to be their VP of innovation and external partnerships. She founded a consulting practice focused on innovation, and her latest endeavor, which she talks about later on in this show, is PharmStars, which is, in my own words, a sort of 10-week crash course/accelerator for digital health start-ups looking to work with Pharma—and for Pharma looking to work with digital health start-ups.

You can learn more about PharmStars at pharmstars.com.

Naomi Fried, PhD, is the founder and CEO of PharmStars, the first and only pharma-focused accelerator for digital health start-ups, dedicated to driving digital health adoption to improve patient outcomes. PharmStars understands and addresses the challenges that Pharma and start-ups face when seeking to collaborate. Its PharmaU™ program supports its digital health start-ups and pharma members seeking to “bridge the gap,” leading to greater success and faster adoption of “beyond the molecule” solutions for patients. PharmStars provides education and mentoring to digital health start-ups seeking engagement with pharma and biotech firms. Its pharma members are committed to working with its graduating start-ups. Applications for participation in the first cohort are due July 21, 2021.

Dr. Fried is also the co-founder and managing partner of Ambit Health Ventures, an early-stage venture capital fund focused on digital health investments. Previously, she was the CEO of the consulting firm Health Innovation Strategies, VP of innovation and external partnerships at Biogen, the first chief innovation officer at Boston Children’s Hospital, and the first VP of innovation and advanced technology at Kaiser Permanente. She advises and serves on the boards of digital health start-ups.


03:42 What does the pharma–start-up gap look like?
05:49 Why is it hard to navigate Big Pharma when trying to partner with start-ups?
09:53 “A lot of what contributes to that pharma–start-up gap is a lack of understanding.”
10:05 What’s the best way to navigate the pharma–start-up partnership?
10:55 “There’s not a clear path as to who should be engaged from the pharma side, because the value proposition wasn’t well articulated.”
12:27 “Even if … the product is better, if it’s such an uphill battle to get them through the hoops and to work with them, they may not be the partner of choice.”
13:45 Why are start-ups surprised at who all is involved with the decision-making process on the pharma side?
15:51 Where might start-ups run into regulatory oversight compliance issues?
20:41 “Setting expectations and talking early on … really, just understanding on both sides … they have to meet each other and work around these requirements.”
22:02 “Start-ups really are under financial pressure.”
26:33 “Pharma has a lot to offer digital health start-ups.”
27:40 Is Pharma any good at selling something to a provider?
29:22 What do start-ups need to keep in mind when pitching to Pharma?
30:35 “Understanding Pharma’s needs, how they work, what they will pay for is so important for start-ups.”

You can learn more about PharmStars at pharmstars.com.

healthcare,pharma,digital health,health tech,pharmstars,health startups,
|

Episode Support Provided By

Special Thanks to Our 2026 Sustaining Monthly Donors

Kimberly CarlesonDylan YahnBenjamin LightMatt McQuideAnn KempskiSpencer AllenScott TromanhauserMarilyn BartlettSteven ElkinsMatthew Bunte.

Recent Episodes

EP505: The Death of the "What Is Value" Guessing Game for Clinical and Plan Decision-Makers Ready to Move On, With Ahilan Sivaganesan, MD
Relentless Health ValueApril 02, 2026
505
44:0240.31 MB

EP505: The Death of the "What Is Value" Guessing Game for Clinical and Plan Decision-Makers Ready to Move On, With Ahilan Sivaganesan, MD

Listen On Your Favorite App Hello, Relentless Tribe. Thank you so much for showing up today. All right … to start, let me lay out the goal of the episode today. This episode is for you if you are a self-funded employer looking to ensure your members are steered and tiered to real high-value care and...

EP504: A Back-to-Basics Roadmap Through the Perverse Incentives to Advanced Primary Care, With Ryan Jacobs
Relentless Health ValueMarch 26, 2026
504
33:3630.76 MB

EP504: A Back-to-Basics Roadmap Through the Perverse Incentives to Advanced Primary Care, With Ryan Jacobs

Listen On Your Favorite App It's been a while since we started from the beginning, so let's just take stock of the basics in this show, refresh ourselves if you're a longtime listener, or welcome if you're new around here. Today we are digging on and about what I would call the poster child for prov...

INBW46: Relentless Tribe Goings-On With Insights to Outwit the Hot Mess of the Non-Healthcare Market
Relentless Health ValueMarch 19, 202619:3717.96 MB

INBW46: Relentless Tribe Goings-On With Insights to Outwit the Hot Mess of the Non-Healthcare Market

Listen On Your Favorite App This inbetweenisode I wanna try something new for two reasons. One of them is that I need to check this episode off my to-do list because I am crushed for time. I'm going to be headed to Arizona tomorrow for the Collective Health Conference , which will have occurred thre...

EP503: Let's Go From Lazy PPO Networks to Smart Collaboration With Direct-to-Employer Specialty Care, With Ryan Wells; Leo Spector, MD, MBA; and Adam Stavisky
Relentless Health ValueMarch 12, 2026
503
46:1642.35 MB

EP503: Let's Go From Lazy PPO Networks to Smart Collaboration With Direct-to-Employer Specialty Care, With Ryan Wells; Leo Spector, MD, MBA; and Adam Stavisky

Listen On Your Favorite App Today we are digging into something I've said probably way too often: Collaboration is the next breakthrough innovation. And I'm doubling down on this because in the current healthcare landscape, two parties that actually should be talking—like burning up the phone wires ...

EP502: How Some Pretty Wild Medicare Fraud Sabotages ACOs and Also Independent Practices and Could Cost Plan Sponsors Such as Self-insured Employers a Lot of Zeros Downstream, With Brian Machut
Relentless Health ValueMarch 05, 2026
502
38:5835.67 MB

EP502: How Some Pretty Wild Medicare Fraud Sabotages ACOs and Also Independent Practices and Could Cost Plan Sponsors Such as Self-insured Employers a Lot of Zeros Downstream, With Brian Machut

You know, I always kind of wondered what the hackers were doing with all of the medical data that they've managed to get their mitts on over the past, I don't know, however many years. Now, I know at least one thing. If you're a hacker, you can use your stolen medical data to not actually send wildl...

EP501: Speaking of Infusions, Do You Want to Pay $135 or Do You Want to Pay $13,560 for the Exact Same Drug? With Ivana Krajcinovic, PhD
Relentless Health ValueFebruary 26, 2026
501
39:5736.57 MB

EP501: Speaking of Infusions, Do You Want to Pay $135 or Do You Want to Pay $13,560 for the Exact Same Drug? With Ivana Krajcinovic, PhD

Let us chat about today the inches all around us and also about how there is no market in healthcare all at once in this show. Today I am talking with Ivana Krajcinovic. And let me give you some examples of the inches. Two members of a plan get infusions at a hospital. And if these two members had g...

Take Two: EP398: Why Are Commercial Carrier Marketplaces Completely Boring? Maybe Because There Isn't a Marketplace, With Jacob Asher, MD
Relentless Health ValueFebruary 19, 202634:5231.91 MB

Take Two: EP398: Why Are Commercial Carrier Marketplaces Completely Boring? Maybe Because There Isn't a Marketplace, With Jacob Asher, MD

We have been doing a little series called "The Inches Are All Around Us," digging out waste in the $5.6 trillion healthcare sector where half an inch of waste can equal billions of dollars. I'm going to right now introduce another series that is complementary but has a slightly different focus. And ...

Listen and Follow

Sponsored by Aventria Health Group
©2026 BD Bridges LLC. All Rights Reserved.